Jagged1-mediated myeloid Notch1 signaling activates HSF1/Snail and controls NLRP3 inflammasome activation in liver inflammatory injury

Notch signaling plays important roles in the regulation of immune cell functioning during the inflammatory response. Activation of the innate immune signaling receptor NLRP3 promotes inflammation in injured tissue. However, it remains unknown whether Jagged1 (JAG1)-mediated myeloid Notch1 signaling...

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Detalhes bibliográficos
Publicado no:Cell Mol Immunol
Main Authors: Jin, Yuting, Li, Changyong, Xu, Dongwei, Zhu, Jianjun, Wei, Song, Zhong, Andrew, Sheng, Mingwei, Duarte, Sergio, Coito, Ana J., Busuttil, Ronald W., Xia, Qiang, Kupiec-Weglinski, Jerzy W., Ke, Bibo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7784844/
https://ncbi.nlm.nih.gov/pubmed/31673056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-019-0318-x
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