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Cyclic nucleotide selectivity of protein kinase G isozymes

The intrinsic activity of the C‐terminal catalytic (C) domain of cyclic guanosine monophosphate (cGMP)‐dependent protein kinases (PKG) is inhibited by interactions with the N‐terminal regulatory (R) domain. Selective binding of cGMP to cyclic nucleotide binding (CNB) domains within the R‐domain disr...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Kim, Choel, Sharma, Rajesh
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7784742/
https://ncbi.nlm.nih.gov/pubmed/33271627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.4008
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