Targeting phosphoglycerate dehydrogenase in multiple myeloma

BACKGROUND: Multiple myeloma (MM) is a hematological malignancy characterized by the clonal expansion of plasma cells in the bone marrow. To date, this disease is still incurable and novel therapeutic approaches are required. Phosphoglycerate dehydrogenase (PHGDH) is the first and rate-limiting enzy...

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Detalles Bibliográficos
Publicado en:Exp Hematol Oncol
Autores principales: Elsaadi, Samah, Steiro, Ida, Abdollahi, Pegah, Vandsemb, Esten N., Yang, Rui, Slørdahl, Tobias S., Rø, Torstein Baade, Menu, Eline, Sponaas, Anne-Marit, Børset, Magne
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7784327/
https://ncbi.nlm.nih.gov/pubmed/33397437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-020-00196-w
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