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Targeting phosphoglycerate dehydrogenase in multiple myeloma

BACKGROUND: Multiple myeloma (MM) is a hematological malignancy characterized by the clonal expansion of plasma cells in the bone marrow. To date, this disease is still incurable and novel therapeutic approaches are required. Phosphoglycerate dehydrogenase (PHGDH) is the first and rate-limiting enzy...

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Detalhes bibliográficos
Publicado no:Exp Hematol Oncol
Main Authors: Elsaadi, Samah, Steiro, Ida, Abdollahi, Pegah, Vandsemb, Esten N., Yang, Rui, Slørdahl, Tobias S., Rø, Torstein Baade, Menu, Eline, Sponaas, Anne-Marit, Børset, Magne
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7784327/
https://ncbi.nlm.nih.gov/pubmed/33397437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-020-00196-w
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