Targeting phosphoglycerate dehydrogenase in multiple myeloma

BACKGROUND: Multiple myeloma (MM) is a hematological malignancy characterized by the clonal expansion of plasma cells in the bone marrow. To date, this disease is still incurable and novel therapeutic approaches are required. Phosphoglycerate dehydrogenase (PHGDH) is the first and rate-limiting enzy...

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Dettagli Bibliografici
Pubblicato in:Exp Hematol Oncol
Autori principali: Elsaadi, Samah, Steiro, Ida, Abdollahi, Pegah, Vandsemb, Esten N., Yang, Rui, Slørdahl, Tobias S., Rø, Torstein Baade, Menu, Eline, Sponaas, Anne-Marit, Børset, Magne
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7784327/
https://ncbi.nlm.nih.gov/pubmed/33397437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-020-00196-w
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