Targeting phosphoglycerate dehydrogenase in multiple myeloma

BACKGROUND: Multiple myeloma (MM) is a hematological malignancy characterized by the clonal expansion of plasma cells in the bone marrow. To date, this disease is still incurable and novel therapeutic approaches are required. Phosphoglycerate dehydrogenase (PHGDH) is the first and rate-limiting enzy...

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Dades bibliogràfiques
Publicat a:Exp Hematol Oncol
Autors principals: Elsaadi, Samah, Steiro, Ida, Abdollahi, Pegah, Vandsemb, Esten N., Yang, Rui, Slørdahl, Tobias S., Rø, Torstein Baade, Menu, Eline, Sponaas, Anne-Marit, Børset, Magne
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7784327/
https://ncbi.nlm.nih.gov/pubmed/33397437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-020-00196-w
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