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Electron Redistribution within the Nitrogenase Active Site FeMo-Cofactor During Reductive Elimination of H(2) to Achieve N≡N Triple-Bond Activation

Nitrogen fixation by nitrogenase begins with the accumulation of four reducing equivalents at the active-site FeMo-cofactor (FeMo-co), generating a state (denoted E(4)(4H)) with two [Fe─H─Fe] bridging hydrides. Recently, photolytic reductive elimination (re) of the E(4)(4H) hydrides showed that enzy...

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Détails bibliographiques
Publié dans:J Am Chem Soc
Auteurs principaux: Lukoyanov, Dmitriy A, Yang, Zhi-Yong, Dean, Dennis R., Seefeldt, Lance C., Raugei, Simone, Hoffman, Brian M.
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7783777/
https://ncbi.nlm.nih.gov/pubmed/33326225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c07914
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