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Fueling chimeric antigen receptor T cells with cytokines

Chimeric antigen receptor (CAR)-T therapy started a new era of tumor treatment, especially for hematological malignancies. However, many challenges remain, including low-level proliferation and short-term persistence, insufficient CAR T-cell trafficking, suppressive tumor microenvironment (TME), fre...

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Détails bibliographiques
Publié dans:Am J Cancer Res
Auteurs principaux: Jin, Jin, Cheng, Jiali, Huang, Meijuan, Luo, Hui, Zhou, Jianfeng
Format: Artigo
Langue:Inglês
Publié: e-Century Publishing Corporation 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7783740/
https://ncbi.nlm.nih.gov/pubmed/33414984
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