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Chimeric antigen receptor–T cells with cytokine neutralizing capacity
Infusion of T lymphocytes expressing chimeric antigen receptors (CARs) can produce extraordinary antitumor activity in patients with leukemia, lymphoma, and myeloma. The signaling mechanisms activating T cells and provoking tumor cell killing also trigger cytokine secretion and macrophage activation...
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| Publicado no: | Blood Adv |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7160280/ https://ncbi.nlm.nih.gov/pubmed/32271901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019001287 |
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