Comprehensive analysis of transcriptomics and metabolomics to understand triptolide-induced liver injury in mice

Triptolide, a major active component of Triptergium wilfordii Hook. f, is used in the treatment of autoimmune disease. However, triptolide is associated with severe adverse reactions, especially hepatotoxicity, which limits its clinical application. To examine the underlying mechanism of triptolide-...

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Detalhes bibliográficos
Publicado no:Toxicol Lett
Main Authors: Zhao, Jie, Xie, Cen, Wang, Kanglong, Takahashi, Shogo, Krausz, Kristopher W., Lu, Dasheng, Wang, Qiong, Luo, Yuhong, Gong, Xianqiong, Mu, Xiyan, Wang, Qiao, Su, Suwen, Gonzalez, Frank J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7783549/
https://ncbi.nlm.nih.gov/pubmed/32835833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2020.08.007
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