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A comprehensive understanding of thio TEPA metabolism in the mouse using UPLC-ESI-QTOFMS-based metabolomics
ThioTEPA, an alkylating agent with anti-tumor activity, has been used as an effective anticancer drug since the 1950s. However, a complete understanding of how its alkylating activity relates to clinical efficacy has not been achieved, the total urinary excretion of thioTEPA and its metabolites is n...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Biochem Pharmacol |
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| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2011
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6309239/ https://ncbi.nlm.nih.gov/pubmed/21300029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2011.01.024 |
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