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Transcriptome Analysis of K-877 (a Novel Selective PPARα Modulator (SPPARMα))-Regulated Genes in Primary Human Hepatocytes and the Mouse Liver

AIM: Selective PPARα modulators (SPPARMα) are under development for use as next-generation lipid lowering drugs. In the current study, to predict the pharmacological and toxicological effects of a novel SPPARMα K-877, comprehensive transcriptome analyses of K-877-treated primary human hepatocytes an...

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Detalhes bibliográficos
Publicado no:J Atheroscler Thromb
Main Authors: Raza-Iqbal, Sana, Tanaka, Toshiya, Anai, Motonobu, Inagaki, Takeshi, Matsumura, Yoshihiro, Ikeda, Kaori, Taguchi, Akashi, Gonzalez, Frank J., Sakai, Juro, Kodama, Tatsuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7783548/
https://ncbi.nlm.nih.gov/pubmed/26040752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5551/jat.28720
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