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PPARα activation directly upregulates thrombomodulin in the diabetic retina
Two large clinical studies showed that fenofibrate, a commonly used peroxisome proliferator-activated receptor α (PPARα) agonist, has protective effects against diabetic retinopathy. However, the underlying mechanism has not been clarified. We performed genome-wide analyses of gene expression and PP...
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| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7331602/ https://ncbi.nlm.nih.gov/pubmed/32616724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67579-1 |
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