A Novel Selective PPARα Modulator (SPPARMα), K-877 (Pemafibrate), Attenuates Postprandial Hypertriglyceridemia in Mice

Aims: Fasting and postprandial hypertriglyceridemia (PHTG) are caused by the accumulation of triglyceride (TG)-rich lipoproteins and their remnants, which have atherogenic effects. Fibrates can improve fasting and PHTG; however, reduction of remnants is clinically needed to improve health outcomes....

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Vydáno v:J Atheroscler Thromb
Hlavní autoři: Sairyo, Masami, Kobayashi, Takuya, Masuda, Daisaku, Kanno, Koutaro, Zhu, Yinghong, Okada, Takeshi, Koseki, Masahiro, Ohama, Tohru, Nishida, Makoto, Sakata, Yasushi, Yamashita, Shizuya
Médium: Artigo
Jazyk:Inglês
Vydáno: Japan Atherosclerosis Society 2018
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827084/
https://ncbi.nlm.nih.gov/pubmed/28781340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5551/jat.39693
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