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Natural Compounds as Inhibitors of Aβ Peptide Aggregation: Chemical Requirements and Molecular Mechanisms

Alzheimer’s disease (AD) is one of the most common neurodegenerative disorders, with no cure and preventive therapy. Misfolding and extracellular aggregation of Amyloid-β (Aβ) peptides are recognized as the main cause of AD progression, leading to the formation of toxic Aβ oligomers and to the depos...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Pagano, Katiuscia, Tomaselli, Simona, Molinari, Henriette, Ragona, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7783407/
https://ncbi.nlm.nih.gov/pubmed/33414705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.619667
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