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Bifunctional Compounds for Controlling Metal-Mediated Aggregation of the Aβ(42) Peptide
Abnormal interactions of Cu and Zn ions with the amyloid β (Aβ) peptide are proposed to play an important role in the pathogenesis of Alzheimer’s disease (AD). Disruption of these metal–peptide interactions using chemical agents holds considerable promise as a therapeutic strategy to combat this inc...
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Asıl Yazarlar: | , , , , , , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
2012
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3368506/ https://ncbi.nlm.nih.gov/pubmed/22452395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja210588m |
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