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The effect of Cu(2+) and Zn(2+) on the Aβ(42) peptide aggregation and cellular toxicity

The coordination chemistry of Cu and Zn metal ions with the amyloid β (Aβ) peptides has attracted a lot of attention in recent years due to its implications in Alzheimer’s disease. A number of reports indicate that Cu and Zn have profound effects on Aβ aggregation. However, the impact of these metal...

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Detalhes bibliográficos
Main Authors: Sharma, Anuj K., Pavlova, Stephanie T., Kim, Jaekwang, Kim, Jungsu, Mirica, Liviu M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060528/
https://ncbi.nlm.nih.gov/pubmed/23995980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3mt00161j
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