ZNF143 mediates CTCF-bound promoter–enhancer loops required for murine hematopoietic stem and progenitor cell function

CCCTC binding factor (CTCF) is an important factor in the maintenance of chromatin–chromatin interactions, yet the mechanism regulating its binding to chromatin is unknown. We demonstrate that zinc finger protein 143 (ZNF143) is a key regulator for CTCF-bound promoter–enhancer loops. In the murine g...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Zhou, Qiling, Yu, Miao, Tirado-Magallanes, Roberto, Li, Bin, Kong, Lingshi, Guo, Mingrui, Tan, Zi Hui, Lee, Sanghoon, Chai, Li, Numata, Akihiko, Benoukraf, Touati, Fullwood, Melissa Jane, Osato, Motomi, Ren, Bing, Tenen, Daniel G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7782510/
https://ncbi.nlm.nih.gov/pubmed/33397967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20282-1
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