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Guanine nucleotide exchange factors activate Rab8a for Toll-like receptor signalling

Macrophages are important immune sentinels that detect and clear pathogens and initiate inflammatory responses through the activation of surface receptors, including Toll-like receptors (TLRs). Activated TLRs employ complex cellular trafficking and signalling pathways to initiate transcription for i...

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Publicat a:Small GTPases
Autors principals: Tong, Samuel J., Wall, Adam A., Hung, Yu, Luo, Lin, Stow, Jennifer L.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7781844/
https://ncbi.nlm.nih.gov/pubmed/30843452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2019.1587278
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