Potent in vitro anti-SARS-CoV-2 activity by gallinamide A and analogues via inhibition of cathepsin L

The emergence of SARS-CoV-2 in late 2019, and the subsequent COVID-19 pandemic, has led to substantial mortality, together with mass global disruption. There is an urgent need for novel antiviral drugs for therapeutic or prophylactic application. Cathepsin L is a key host cysteine protease utilized...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:bioRxiv
Glavni autori: Ashhurst, Anneliese S., Tang, Arthur H., Fajtová, Pavla, Yoon, Michael, Aggarwal, Anupriya, Stoye, Alexander, Larance, Mark, Beretta, Laura, Drelich, Aleksandra, Skinner, Danielle, Li, Linfeng, Meek, Thomas D., McKerrow, James H., Hook, Vivian, Tseng, Chien-Te K., Turville, Stuart, Gerwick, William H., O’Donoghue, Anthony J., Payne, Richard J.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory 2020
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7781308/
https://ncbi.nlm.nih.gov/pubmed/33398273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.12.23.424111
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items