Designer Receptors Exclusively Activated by Designer Drugs Approach to Treatment of Sleep-disordered Breathing

Rationale: Obstructive sleep apnea is recurrent upper airway obstruction caused by a loss of upper airway muscle tone during sleep. The main goal of our study was to determine if designer receptors exclusively activated by designer drugs (DREADD) could be used to activate the genioglossus muscle as...

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Detaylı Bibliyografya
Yayımlandı:Am J Respir Crit Care Med
Asıl Yazarlar: Fleury Curado, Thomaz, Pho, Huy, Freire, Carla, Amorim, Mateus R., Bonaventura, Jordi, Kim, Lenise J., Lee, Rachel, Cabassa, Meaghan E., Streeter, Stone R., Branco, Luiz G., Sennes, Luiz U., Fishbein, Kenneth, Spencer, Richard G., Schwartz, Alan R., Brennick, Michael J., Michaelides, Michael, Fuller, David D., Polotsky, Vsevolod Y.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Thoracic Society 2021
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7781140/
https://ncbi.nlm.nih.gov/pubmed/32673075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.202002-0321OC
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