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Late‐Onset Tay‐Sachs Disease in an Irish Family

BACKGROUND: Late‐onset Tay‐Sachs disease (LOTS) is an autosomal‐recessive lysosomal storage disease caused by deficient β‐hexosaminidase A activity. LOTS is rare in the Ashkenazi Jews, but even rarer in the non‐Jewish population. CASES: We report an Irish family expanding the LOTS phenotype (ataxia,...

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Bibliografiske detaljer
Udgivet i:Mov Disord Clin Pract
Main Authors: Lefter, Stela, O' Mahony, Olivia, Sweeney, Brian, Ryan, Aisling M.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780940/
https://ncbi.nlm.nih.gov/pubmed/33426165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mdc3.13096
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