Drug screening platform using human induced pluripotent stem cell‐derived atrial cardiomyocytes and optical mapping

Current drug development efforts for the treatment of atrial fibrillation are hampered by the fact that many preclinical models have been unsuccessful in reproducing human cardiac physiology and its response to medications. In this study, we demonstrated an approach using human induced pluripotent s...

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Dettagli Bibliografici
Pubblicato in:Stem Cells Transl Med
Autori principali: Gunawan, Marvin G., Sangha, Sarabjit S., Shafaattalab, Sanam, Lin, Eric, Heims‐Waldron, Danielle A., Bezzerides, Vassilios J., Laksman, Zachary, Tibbits, Glen F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Inc. 2020
Soggetti:
Cell‐based Drug Development, Screening, and Toxicology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780813/
https://ncbi.nlm.nih.gov/pubmed/32927497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.19-0440
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