Drug screening platform using human induced pluripotent stem cell‐derived atrial cardiomyocytes and optical mapping

Current drug development efforts for the treatment of atrial fibrillation are hampered by the fact that many preclinical models have been unsuccessful in reproducing human cardiac physiology and its response to medications. In this study, we demonstrated an approach using human induced pluripotent s...

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Detalhes bibliográficos
Publicado no:Stem Cells Transl Med
Principais autores: Gunawan, Marvin G., Sangha, Sarabjit S., Shafaattalab, Sanam, Lin, Eric, Heims‐Waldron, Danielle A., Bezzerides, Vassilios J., Laksman, Zachary, Tibbits, Glen F.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Cell‐based Drug Development, Screening, and Toxicology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780813/
https://ncbi.nlm.nih.gov/pubmed/32927497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.19-0440
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