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Choline kinase alpha impairment overcomes TRAIL resistance in ovarian cancer cells
BACKGROUND: Choline kinase-α (ChoKα/CHKA) overexpression and hyper-activation sustain altered choline metabolism conferring the cholinic phenotype to epithelial ovarian cancer (OC), the most lethal gynecological tumor. We previously proved that CHKA down-modulation reduced OC cell aggressiveness and...
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| Pubblicato in: | J Exp Clin Cancer Res |
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| Autori principali: | , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7780408/ https://ncbi.nlm.nih.gov/pubmed/33390181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01794-6 |
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