Integrated genomic and transcriptomic analysis reveals unique characteristics of hepatic metastases and pro-metastatic role of complement C1q in pancreatic ductal adenocarcinoma

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers due to its high metastasis rate in the liver. However, little is known about the molecular features of hepatic metastases due to difficulty in obtaining fresh tissues and low tumor cellularity. RESULTS: We conduct...

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Dades bibliogràfiques
Publicat a:Genome Biol
Autors principals: Yang, Jianyu, Lin, Ping, Yang, Minwei, Liu, Wei, Fu, Xueliang, Liu, Dejun, Tao, Lingye, Huo, Yanmiao, Zhang, Junfeng, Hua, Rong, Zhang, Zhigang, Li, Yixue, Wang, Liwei, Xue, Jing, Li, Hong, Sun, Yongwei
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780398/
https://ncbi.nlm.nih.gov/pubmed/33397441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02222-w
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