Transcription factor NFAT5 contributes to the glycolytic phenotype rewiring and pancreatic cancer progression via transcription of PGK1

Hypoxia and the hypovascular tumor microenvironment are major hallmarks of pancreatic ductal adenocarcinoma (PDAC), in which glycolysis is of great importance to tumor survival and proliferation. There is little research regarding the role of Nuclear Factor of Activated T Cells 5 (NFAT5) in relation...

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Publicado no:Cell Death Dis
Main Authors: Jiang, Yongsheng, He, Ruizhe, Jiang, Yuhong, Liu, Dejun, Tao, Lingye, Yang, Minwei, Lin, Chaoyi, Shen, Yang, Fu, Xueliang, Yang, Jianyu, Li, Jiao, Huo, Yanmiao, Hua, Rong, Liu, Wei, Zhang, Junfeng, Shen, Baiyong, Zhang, Zhigang, Sun, Yongwei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6906509/
https://ncbi.nlm.nih.gov/pubmed/31827081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2072-5
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