Transcription factor NFAT5 contributes to the glycolytic phenotype rewiring and pancreatic cancer progression via transcription of PGK1

Hypoxia and the hypovascular tumor microenvironment are major hallmarks of pancreatic ductal adenocarcinoma (PDAC), in which glycolysis is of great importance to tumor survival and proliferation. There is little research regarding the role of Nuclear Factor of Activated T Cells 5 (NFAT5) in relation...

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Veröffentlicht in:Cell Death Dis
Hauptverfasser: Jiang, Yongsheng, He, Ruizhe, Jiang, Yuhong, Liu, Dejun, Tao, Lingye, Yang, Minwei, Lin, Chaoyi, Shen, Yang, Fu, Xueliang, Yang, Jianyu, Li, Jiao, Huo, Yanmiao, Hua, Rong, Liu, Wei, Zhang, Junfeng, Shen, Baiyong, Zhang, Zhigang, Sun, Yongwei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6906509/
https://ncbi.nlm.nih.gov/pubmed/31827081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2072-5
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