Integrated genomic and transcriptomic analysis reveals unique characteristics of hepatic metastases and pro-metastatic role of complement C1q in pancreatic ductal adenocarcinoma

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers due to its high metastasis rate in the liver. However, little is known about the molecular features of hepatic metastases due to difficulty in obtaining fresh tissues and low tumor cellularity. RESULTS: We conduct...

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Detalles Bibliográficos
Publicado en:Genome Biol
Main Authors: Yang, Jianyu, Lin, Ping, Yang, Minwei, Liu, Wei, Fu, Xueliang, Liu, Dejun, Tao, Lingye, Huo, Yanmiao, Zhang, Junfeng, Hua, Rong, Zhang, Zhigang, Li, Yixue, Wang, Liwei, Xue, Jing, Li, Hong, Sun, Yongwei
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2021
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780398/
https://ncbi.nlm.nih.gov/pubmed/33397441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02222-w
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