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Integrated genomic and transcriptomic analysis reveals unique characteristics of hepatic metastases and pro-metastatic role of complement C1q in pancreatic ductal adenocarcinoma

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers due to its high metastasis rate in the liver. However, little is known about the molecular features of hepatic metastases due to difficulty in obtaining fresh tissues and low tumor cellularity. RESULTS: We conduct...

詳細記述

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書誌詳細
出版年:Genome Biol
主要な著者: Yang, Jianyu, Lin, Ping, Yang, Minwei, Liu, Wei, Fu, Xueliang, Liu, Dejun, Tao, Lingye, Huo, Yanmiao, Zhang, Junfeng, Hua, Rong, Zhang, Zhigang, Li, Yixue, Wang, Liwei, Xue, Jing, Li, Hong, Sun, Yongwei
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780398/
https://ncbi.nlm.nih.gov/pubmed/33397441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02222-w
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