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Condensin minimizes topoisomerase II‐mediated entanglements of DNA in vivo

The juxtaposition of intracellular DNA segments, together with the DNA‐passage activity of topoisomerase II, leads to the formation of DNA knots and interlinks, which jeopardize chromatin structure and gene expression. Recent studies in budding yeast have shown that some mechanism minimizes the knot...

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Bibliografski detalji
Izdano u:EMBO J
Glavni autori: Dyson, Sílvia, Segura, Joana, Martínez‐García, Belén, Valdés, Antonio, Roca, Joaquim
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780148/
https://ncbi.nlm.nih.gov/pubmed/33155682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020105393
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