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Condensin minimizes topoisomerase II‐mediated entanglements of DNA in vivo
The juxtaposition of intracellular DNA segments, together with the DNA‐passage activity of topoisomerase II, leads to the formation of DNA knots and interlinks, which jeopardize chromatin structure and gene expression. Recent studies in budding yeast have shown that some mechanism minimizes the knot...
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| Gepubliceerd in: | EMBO J |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
John Wiley and Sons Inc.
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7780148/ https://ncbi.nlm.nih.gov/pubmed/33155682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020105393 |
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