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The CAG promoter maintains high‐level transgene expression in HEK293 cells
The vast majority of therapeutic recombinant proteins are produced in mammalian cell lines. However, proteins generated in nonhuman cell lines, such as Chinese hamster ovary (CHO) cells, are decorated with human‐like glycan structures that differ from those of human cells, and these may induce immun...
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| Izdano u: | FEBS Open Bio |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley and Sons Inc.
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7780116/ https://ncbi.nlm.nih.gov/pubmed/33155423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.13029 |
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