Lentiviral Vectors Mediate Long-Term and High Efficiency Transgene Expression in HEK 293T cells

Objectives:Lentiviral vectors have been used successfully to rapidly produce decigram quantities of active recombinant proteins in mammalian cell lines. To optimize the protein production platform, the roles of Ubiquitous Chromatin Opening Element (UCOE), an insulator, and selected promoters were ev...

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Detalhes bibliográficos
Publicado no:Int J Med Sci
Main Authors: Mao, Yingying, Yan, Renhe, Li, Andrew, Zhang, Yanling, Li, Jinlong, Du, Hongyan, Chen, Baihong, Wei, Wenjin, Zhang, Yi, Sumners, Colin, Zheng, Haifa, Li, Hongwei
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2015
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441065/
https://ncbi.nlm.nih.gov/pubmed/26005375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.11270
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