Lentiviral Vectors Mediate Long-Term and High Efficiency Transgene Expression in HEK 293T cells

Objectives:Lentiviral vectors have been used successfully to rapidly produce decigram quantities of active recombinant proteins in mammalian cell lines. To optimize the protein production platform, the roles of Ubiquitous Chromatin Opening Element (UCOE), an insulator, and selected promoters were ev...

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Bibliografiske detaljer
Udgivet i:Int J Med Sci
Main Authors: Mao, Yingying, Yan, Renhe, Li, Andrew, Zhang, Yanling, Li, Jinlong, Du, Hongyan, Chen, Baihong, Wei, Wenjin, Zhang, Yi, Sumners, Colin, Zheng, Haifa, Li, Hongwei
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2015
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Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441065/
https://ncbi.nlm.nih.gov/pubmed/26005375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.11270
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