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Cre/LoxP-HBV plasmids generating recombinant covalently closed circular DNA genome upon transfection
New therapies against hepatitis B virus (HBV) require the elimination of covalently closed circular DNA (cccDNA), the episomal HBV genome. HBV plasmids containing an overlength 1.3-mer genome and bacterial backbone (pHBV1.3) are used in many different models, but do not replicate the unique features...
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| Udgivet i: | Virus Res |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7779077/ https://ncbi.nlm.nih.gov/pubmed/33166564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2020.198224 |
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