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Cre/LoxP-HBV plasmids generating recombinant covalently closed circular DNA genome upon transfection

New therapies against hepatitis B virus (HBV) require the elimination of covalently closed circular DNA (cccDNA), the episomal HBV genome. HBV plasmids containing an overlength 1.3-mer genome and bacterial backbone (pHBV1.3) are used in many different models, but do not replicate the unique features...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Virus Res
Egile Nagusiak: Kruse, Robert L., Legras, Xavier, Barzi, Mercedes
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7779077/
https://ncbi.nlm.nih.gov/pubmed/33166564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2020.198224
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