Inhaled tigecycline is effective against Mycobacterium abscessus in vitro and in vivo

BACKGROUND: Mycobacterium abscessus causes chronic pulmonary infections. Owing to its resistance to most classes of antibiotics, treatment is complex and cure rates are only 45%. Tigecycline is active against M. abscessus, but severe toxicity and the need for IV administration limit its use. OBJECTI...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Principais autores: Pearce, Camron, Ruth, Mike M, Pennings, Lian J, Wertheim, Heiman F L, Walz, Amanda, Hoefsloot, Wouter, Ruesen, Carolien, Muñoz Gutiérrez, Juan, Gonzalez-Juarrero, Mercedes, van Ingen, Jakko
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7778363/
https://ncbi.nlm.nih.gov/pubmed/32294173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkaa110
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