A Tiered Female Ovarian Toxicity Screening Identifies Toxic Effects of Checkpoint Kinase 1 Inhibitors on Murine Growing Follicles

Ovarian toxicity (ovotoxicity) is one of the major side effects of pharmaceutical compounds for women at or before reproductive age. The current gold standard for screening of compounds’ ovotoxicity largely relies on preclinical investigations using whole animals. However, in vivo models are time-co...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Toxicol Sci
Main Authors: Xu, Jingshan, Wang, Yingzheng, Kauffman, Alexandra E, Zhang, Yaqi, Li, Yang, Zhu, Jie, Maratea, Kimberly, Fabre, Kristin, Zhang, Qiang, Woodruff, Teresa K, Xiao, Shuo
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
Assuntos:
Developmental and Reproductive Toxicology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7778340/
https://ncbi.nlm.nih.gov/pubmed/32697846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfaa118
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares