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Doxorubicin Has Dose-Dependent Toxicity on Mouse Ovarian Follicle Development, Hormone Secretion, and Oocyte Maturation

Doxorubicin (DOX), one of the most commonly used anticancer medications, has been reported to affect fertility by damaging ovarian follicles; however, the dose-dependent toxicity of DOX on the dynamic follicle development and oocyte maturation has not been well-defined. Our objective is to determine...

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Publicado en:Toxicol Sci
Autores principales: Xiao, Shuo, Zhang, Jiyang, Liu, Mingjun, Iwahata, Hideyuki, Rogers, Hunter B., Woodruff, Teresa K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6074798/
https://ncbi.nlm.nih.gov/pubmed/28329872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfx047
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