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Doxorubicin Has Dose-Dependent Toxicity on Mouse Ovarian Follicle Development, Hormone Secretion, and Oocyte Maturation

Doxorubicin (DOX), one of the most commonly used anticancer medications, has been reported to affect fertility by damaging ovarian follicles; however, the dose-dependent toxicity of DOX on the dynamic follicle development and oocyte maturation has not been well-defined. Our objective is to determine...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Xiao, Shuo, Zhang, Jiyang, Liu, Mingjun, Iwahata, Hideyuki, Rogers, Hunter B., Woodruff, Teresa K.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6074798/
https://ncbi.nlm.nih.gov/pubmed/28329872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfx047
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