Snx14 proximity labeling reveals a role in saturated fatty acid metabolism and ER homeostasis defective in SCAR20 disease

Fatty acids (FAs) are central cellular metabolites that contribute to lipid synthesis, and can be stored or harvested for metabolic energy. Dysregulation in FA processing and storage causes toxic FA accumulation or altered membrane compositions and contributes to metabolic and neurological disorders...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Datta, Sanchari, Bowerman, Jade, Hariri, Hanaa, Ugrankar, Rupali, Eckert, Kaitlyn M., Corley, Chase, Vale, Gonçalo, McDonald, Jeffrey G., Henne, W. Mike
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2020
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7777019/
https://ncbi.nlm.nih.gov/pubmed/33310904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2011124117
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