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Snx14 proximity labeling reveals a role in saturated fatty acid metabolism and ER homeostasis defective in SCAR20 disease

Fatty acids (FAs) are central cellular metabolites that contribute to lipid synthesis, and can be stored or harvested for metabolic energy. Dysregulation in FA processing and storage causes toxic FA accumulation or altered membrane compositions and contributes to metabolic and neurological disorders...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Datta, Sanchari, Bowerman, Jade, Hariri, Hanaa, Ugrankar, Rupali, Eckert, Kaitlyn M., Corley, Chase, Vale, Gonçalo, McDonald, Jeffrey G., Henne, W. Mike
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7777019/
https://ncbi.nlm.nih.gov/pubmed/33310904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2011124117
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