1305. Comparison of Pharmacokinetics of DSTA4637S, a novel THIOMAB(TM) Antibody-Antibiotic Conjugate, in Patients with Staphylococcus aureus Bacteremia Receiving Standard-of-Care Antibiotics with Pharmacokinetics in Healthy Volunteers

BACKGROUND: DSTA4637S, a THIOMAB(TM) antibody-antibiotic conjugate against Staphylococcus aureus, is a potential therapy for complicated S. aureus bacteremia. Single doses showed favorable safety and pharmacokinetics (PK) in healthy volunteers (HVs). This study compares HV PK results to PK from a Ph...

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Enregistré dans:
Détails bibliographiques
Publié dans:Open Forum Infect Dis
Auteurs principaux: Rymut, Sharon M, Deng, Rong, Owen, Ryan, Saad, Ola, Berhanu, Aklile, Lim, Jeremy, Carrasco-Triguero, Montserrat, Couch, Jessica A, Peck, Melicent C
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Poster Abstracts
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7777007/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofaa439.1488
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