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Exploiting MYC-induced PARPness to target genomic instability in multiple myeloma
Multiple myeloma (MM) is a hematologic malignancy strongly characterized by genomic instability, which promotes disease progression and drug resistance. Since we previously demonstrated that LIG3-dependent repair is involved in the genomic instability, drug resistance and survival of MM cells, we he...
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| Pubblicato in: | Haematologica |
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| Autori principali: | , , , , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Fondazione Ferrata Storti
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7776341/ https://ncbi.nlm.nih.gov/pubmed/32079692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.240713 |
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