1315. No Dose Adjustment of Metformin with Fostemsavir Coadministration Based on Mechanistic Static and Physiologically Based Pharmacokinetic Models

Lignende værker

• 2500. Fostemsavir Drug–Drug Interaction Profile, an Attachment Inhibitor and Oral Prodrug of Temsavir, for Heavily Treatment Experienced HIV-1-Infected Patients
  af: Moore, Katy P, et al.
  Udgivet: (2019)
• Pharmacokinetics of Temsavir, the Active Moiety of the Prodrug Fostemsavir, in Subjects with Hepatic Impairment
  af: Sevinsky, Heather, et al.
  Udgivet: (2017)
• Effects of Temsavir, Active Moiety of Antiretroviral Agent Fostemsavir, on QT Interval: Results From a Phase I Study and an Exposure–Response Analysis
  af: Lagishetty, Chakradhar, et al.
  Udgivet: (2020)
• Methadone and buprenorphine pharmacokinetics and pharmacodynamics when coadministered with fostemsavir to opioid‐dependent, human immunodeficiency virus seronegative participants
  af: Moore, Katy, et al.
  Udgivet: (2019)
• Effect of centchroman coadministration on the pharmacokinetics of metformin in rats
  af: Lal, Jawahar, et al.
  Udgivet: (2010)