A Multicohort Open-label Phase II Trial of Bipolar Androgen Therapy in Men with Metastatic Castration-resistant Prostate Cancer (RESTORE): A Comparison of Post-abiraterone Versus Post-enzalutamide Cohorts

BACKGROUND: Cyclic high-dose testosterone injections, also known as bipolar androgen therapy (BAT), is a novel treatment strategy for patients with metastatic castration-resistant prostate cancer (mCRPC). BAT has shown clinical activity in prior studies enrolling men with mCRPC and may potentially r...

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Vydáno v:Eur Urol
Hlavní autoři: Markowski, Mark C., Wang, Hao, Sullivan, Rana, Rifkind, Irina, Sinibaldi, Victoria, Schweizer, Michael T., Teply, Benjamin A., Ngomba, Nduku, Fu, Wei, Carducci, Michael A., Paller, Channing J., Marshall, Catherine H., Eisenberger, Mario A., Luo, Jun, Antonarakis, Emmanuel S., Denmeade, Samuel R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7775877/
https://ncbi.nlm.nih.gov/pubmed/32624280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2020.06.042
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