Co-Delivery of Peptide Neoantigens and Stimulator of Interferon Genes (STING) Agonists Enhances Response to Cancer Vaccines

Cancer vaccines targeting patient-specific neoantigens have emerged as a promising strategy for improving responses to immune checkpoint blockade. However, neoantigenic peptides are poorly immunogenic and inept at stimulating CD8(+) T cell responses, motivating a need for new vaccine technologies th...

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Publicado no:ACS Nano
Main Authors: Shae, Daniel, Baljon, Jessalyn J., Wehbe, Mohamed, Christov, Plamen P., Becker, Kyle W., Kumar, Amrendra, Suryadevara, Naveenchandra, Carson, Carcia S., Palmer, Christian R., Knight, Frances C., Joyce, Sebastian, Wilson, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7775800/
https://ncbi.nlm.nih.gov/pubmed/32701257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.0c02765
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