BBB pathophysiology–independent delivery of siRNA in traumatic brain injury

Small interfering RNA (siRNA)–based therapeutics can mitigate the long-term sequelae of traumatic brain injury (TBI) but suffer from poor permeability across the blood-brain barrier (BBB). One approach to overcoming this challenge involves treatment administration while BBB is transiently breached a...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Li, Wen, Qiu, Jianhua, Li, Xiang-Ling, Aday, Sezin, Zhang, Jingdong, Conley, Grace, Xu, Jun, Joseph, John, Lan, Haoyue, Langer, Robert, Mannix, Rebekah, Karp, Jeffrey M., Joshi, Nitin
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7775748/
https://ncbi.nlm.nih.gov/pubmed/33523853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abd6889
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