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Intrabladder PAC1 receptor antagonist, PACAP(6–38), reduces urinary bladder frequency and pelvic sensitivity in mice exposed to repeated variate stress (RVS)

Stress causes symptom exacerbation in functional disorders of the urinary bladder. However, the potential mediators and underlying mechanisms of stress effects on micturition reflex function are unknown. We have characterized PACAP (Adcyap1) and PAC1 receptor (Adcyap1r1) signaling in stress-induced...

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Detalhes bibliográficos
Publicado no:J Mol Neurosci
Main Authors: Girard, Beatrice M., Campbell, Susan E., Beca, Katharine I., Perkins, Megan, Hsiang, Harrison, May, Victor, Vizzard, Margaret A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7775277/
https://ncbi.nlm.nih.gov/pubmed/32613552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-020-01649-x
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