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Intravesical PAC1 Receptor Antagonist, PACAP(6–38), Reduces Urinary Bladder Frequency and Pelvic Sensitivity in NGF-OE Mice

Chronic NGF overexpression (OE) in the urothelium, achieved through the use of a highly urothelium-specific uroplakin II promoter, stimulates neuronal sprouting in the urinary bladder, produces increased voiding frequency and non-voiding contractions, and referred somatic sensitivity. Additional NGF...

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Detalhes bibliográficos
Publicado no:J Mol Neurosci
Main Authors: Girard, Beatrice M., Malley, Susan E., Mathews, Morgan M., May, Victor, Vizzard, Margaret A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5252828/
https://ncbi.nlm.nih.gov/pubmed/27146136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-016-0764-1
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