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Intrabladder PAC1 receptor antagonist, PACAP(6–38), reduces urinary bladder frequency and pelvic sensitivity in mice exposed to repeated variate stress (RVS)

Stress causes symptom exacerbation in functional disorders of the urinary bladder. However, the potential mediators and underlying mechanisms of stress effects on micturition reflex function are unknown. We have characterized PACAP (Adcyap1) and PAC1 receptor (Adcyap1r1) signaling in stress-induced...

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Dades bibliogràfiques
Publicat a:J Mol Neurosci
Autors principals: Girard, Beatrice M., Campbell, Susan E., Beca, Katharine I., Perkins, Megan, Hsiang, Harrison, May, Victor, Vizzard, Margaret A.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7775277/
https://ncbi.nlm.nih.gov/pubmed/32613552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-020-01649-x
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