Enzyme Inhibitory Kinetics and Molecular Docking Studies of Halo-Substituted Mixed Ester/Amide-Based Derivatives as Jack Bean Urease Inhibitors

A series of halo-substituted mixed ester/amide-based analogues 4a-l have been prepared as jack bean urease inhibitor, which showed good to excellent inhibition of enzyme activity. The role of halo-substituted benzoyl moieties and alkyl substituted anilines in urease inhibitory kinetics was also inve...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Rashid, Muhammad, Rafique, Hummera, Roshan, Sadia, Shamas, Shazia, Iqbal, Zafar, Ashraf, Zaman, Abbas, Qamar, Hassan, Mubashir, Qureshi, Zia Ur Rahman, Asad, Muhammad Hassham Hassan Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7775144/
https://ncbi.nlm.nih.gov/pubmed/33426080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8867407
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