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Sulfonamide-Linked Ciprofloxacin, Sulfadiazine and Amantadine Derivatives as a Novel Class of Inhibitors of Jack Bean Urease; Synthesis, Kinetic Mechanism and Molecular Docking

Sulfonamide derivatives serve as an important building blocks in the drug design discovery and development (4D) process. Ciprofloxacin-, sulfadiazine- and amantadine-based sulfonamides were synthesized as potent inhibitors of jack bean urease and free radical scavengers. Molecular diversity was expl...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Channar, Pervaiz Ali, Saeed, Aamer, Albericio, Fernando, Larik, Fayaz Ali, Abbas, Qamar, Hassan, Mubashir, Raza, Hussain, Seo, Sung-Yum
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152116/
https://ncbi.nlm.nih.gov/pubmed/28813027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22081352
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