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Sulfonamide-Based Azaheterocyclic Schiff Base Derivatives as Potential Carbonic Anhydrase Inhibitors: Synthesis, Cytotoxicity, and Enzyme Inhibitory Kinetics
A series of sulfonamide-bearing azaheterocyclic Schiff base derivatives 3(a-j) were synthesized as carbonic anhydrase inhibitors. The substituted benzene sulfonyl chlorides 1(a-d) were reacted with N(2)H(4) to get aromatic sulfonyl hydrazides 2(a-d). The intermediate hydrazides 2(a-d) were treated w...
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| Udgivet i: | Biomed Res Int |
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| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Hindawi
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7054763/ https://ncbi.nlm.nih.gov/pubmed/32149140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8104107 |
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