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Direct Radiofluorination of Arene C–H Bonds via Photoredox Catalysis Using a Peroxide as the Terminal Oxidant

Herein, we describe an organic photoredox system for direct arene C–H radiofluorination using a peroxide oxidizing agent and LEDs as the light source. In conjunction with an optimized photocatalyst and a microtubing reactor, this system is applicable to a range of electron-rich aromatics and heteroa...

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Bibliographic Details
Published in:Org Lett
Main Authors: Wang, Li, White, Alexander R., Chen, Wei, Wu, Zhanhong, Nicewicz, David A., Li, Zibo
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7774802/
https://ncbi.nlm.nih.gov/pubmed/33000949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.0c02815
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